Indane-1.3-dioeneis an importnat organic compound known for its anticoagulant and anthelmintic activities.This book provides the simple methid of syntheis of indane-1,3-dione and synthesis of hydrazones and crrbazones.In part II incorporation of benzimdazole which is another importnat pharmacophore into indane-1,3-dione has been given.The users of this book will be provided with novel synthetic routes for the synthesis of novel organic compounds bearing indane-1,3-dione.Also the anticoagulant activity screening has been carried out by simple method.