Original Formula Nature Made TripleFlex ® Triple Strength* is full of joint-healthy essentials that promote overall long-term joint health and comfort. Nature Made TripleFlex Triple Strength is a blend of three key ingredients to keep your joints healthy in two caplets daily. Glucosamine to support and protect strong cartilage, Chondroitin to provide a cushion for joints, and MSM to promote joint strength and flexibility.