These forty-two papers are dedicated to Lellia Ruggini (1959-2002), widely renowned for her research on the relationship between Jews, Christians and pagans in Late Antiquity and especially in Italy. The papers are divided into six major subject areas: Italy, elites and their culture, Christianity and the Church, the economy and society, administration, ancient and modern historiography. The papers, in Spanish, Italian, French and English cover a broad spectrum of topics, including studies of ceramics, iconography, coinage, Augustine and the early Christian Church, political speeches, letters, the imperial calendar, epigraphy and archaeological evidence.