Patogeneticheskaya effektivnost" kompleksnogo lecheniya osteoartroza: Diagnosticheskaya tsennost" biomarkerov (Russian Edition)

Osteoartroz priobretaet vse bol"shuyu znachimost" dlya zdravookhraneniya,poskol"ku v obshchestve uvelichivaetsya dolya pozhilykh lyudey. Sledovatel"no, problemy diagnostiki i lecheniya dannogo zabolevaniya vyzyvayut bol"shoy interes. Izvestno,chto kharakternym priznakom destruktsii khryashcha pri osteoartroze yavlyaetsya poterya matriksom glikozaminoglikanov, chto privodit k dezorganizatsii razryvu kollagenovykh volokon. V poslednie gody vedetsya intensivnyy poisk vozmozhnykh biologicheskikh markerov degradatsii i reparatsii tkaney sustava. Nekotorye biomarkery v syvorotke krovi opredelyayut uzhe segodnya – glikozaminoglikany, oligomernyy matriksnyy protein khryashcha (COMP)i dr.,chto mozhno ispol"zovat" v kachestve kriteriya effektivnosti v klinicheskikh issledovaniyakh kak medikamentoznykh, tak i nemedikamentoznykh metodov lecheniya, a takzhe dlya monitorirovaniya patogeneticheskoy terapii. V dannoy knige prodemonstrirovano issledovanie pokazateley glikozaminoglikanov syvorotki krovi u bol"nykh osteoartrozom. Obosnovana kompleksnaya skhema lecheniya osteoartroza –traditsionnaya terapiya s primeneniem nizkointensivnogo lazernogo izlucheniya. Dokazana klinicheskaya effektivnost" lazernoy terapii na fone snizheniya soderzhaniya glikozaminoglikanov