Viral hepatitis is liver inflammation due to a viral infection. It may be present in recent infection, relatively rapid onset (acute) or long-lasting (chronic) forms. The most common causes of viral hepatitis are the hepatotropic viruses whose primary tissue tropism is the liver. In human, at least five hepatitis viruses are named alphabetically: hepatitis A (HAV), hepatitis B (HBV), hepatitis C (HCV), hepatitis D(HDV) and hepatitis E (HEV). Hepatitis B virus (HBV) infection is one of the major global health problems that cause acute and chronic hepatitis in human. Chronic HBV in infection is most commonly defined as as chronic necroinflammatory disease hepatitis A (HAV), hepatitis B (HBV), hepatitis C (HCV), hepatitis D(HDV) and hepatitis E (HEV). Hepatitis B virus (HBV) infection is one of the major global health problems that cause acute and chronic hepatitis in human. Chronic HBV in infection is most commonly defined as as chronic necroinflammatory disease