Mukovistsidoz - naibolee chastoe geneticheskoe zabolevanie, kharakterizuyushcheesya porazheniem ekzokrinnykh zhelez zhiznenno vazhnykh organov i sistem i imeyushchee, kak pravilo, tyazheloe techenie i prognoz. V poslednee vremya zametno vozros interes issledovateley k probleme porazheniya pochek u detey s mukovistsidozom. Vsledstvie uvelicheniya prodolzhitel"nosti zhizni takikh patsientov, izmeneniya so storony pochek, a takzhe diagnostika i terapiya dannykh narusheniy priobretayut vse bol"shee klinicheskoe znachenie. Avtorom provedena otsenka vliyaniya mikroflory nizhnikh dykhatel"nykh putey na razvitie pochechnoy patologii pri mukovistsidoze. Ustanovleno, chto u detey s mukovistsidozom s uvelicheniem tyazhesti i dlitel"nosti zabolevaniya narastaet vyrazhennost" funktsional"nykh narusheniy pochek, osobenno u bol"nykh so smeshannoy formoy zabolevaniya. Pokazano, chto pri smeshannoy forme i tyazhelom techenii mukovistsidoza otmecheny kak narusheniya klubochkovoy fil"tratsii, tak i kanal"tsevoy reabsorbtsii. Opisany varianty pochechnoy patologii u obsledovannykh patsientov i predlozhen kompleks meropriyatiy po profilaktike i ranney diagnostike podobnykh oslozhneniy. Kniga prednaznachena dlya vrachey pediatrov, bakteriologov, spetsialistov tsentrov po lecheniyu mukovistsidoza.