Self Emulsifying Drug Delivery Systems: A Formulation Approach for Poorly Soluble Drugs
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Self emulsifying drug delivery systems, which are by no means a recent technological innovation, have not only proven their utility for mitigating the poor and variable gastrointestinal absorption of lipophilic drugs, but in many cases have shown the ability to reduce or eliminate the influence of food on the absorption of these drugs. A cursory review of literature will clearly underscore not only scientific interest in Self-Emulsifying formulations, but will reinforce the promise and versatility that this technology holds for addressing the constant and growing problems surrounding the oral delivery of many poorly soluble drug candidates. This book seeks to provide a comprehensive summary of both the theoretical and practical aspects of oral self-emulsifying formulations to formulators wishing to employ the technology as well as scientific and marketing executives who wish to gain a greater understanding of developing technology that is expected to assume increasing prominence in the years to come. It is the author’s hope that the concepts and techniques described in this book will lead to the development of improved dosage forms for water-insoluble drugs.