Diindolylmethane (DIM) is a natural compound formed during the breakdown of plants and the digestion of indole-3-carbinol, from the Brassica genus of plants. Some of the vegetables of this genus include, broccoli, cabbage, Brussels sprouts, cauliflower, and kale. In fact, many of the positive health-promoting benefits of these vegetables are due to the activity of DIM in the body. Both men and women use DIM to support healthy estrogen metabolism and hormonal balance in the body.