Clean thoroughly at least twice a day or as recommended by a dentist. Children under 6 years should be under the supervision of an adult and use a pea sized amount to minimize risk of swallowing. If you are taking fluoride from other sources, consult a dentist or doctor. Do not swallow. Children should thoroughly rinse after cleaning the mouth and spit out. Manufactured by Colgate-Palmolive (China) for the European market. 75ml tube