This book starts from simplest operation and rudimentary concepts to introduce Visual Basic.Net2010 programming. The book elaborates basic programming and techniques by uniting most fundamental contents and rich examples and introduces VB.NET language foundation, basic control structure of program, process, user interface design, common dialog box and menu, object oriented programming, access to database, debugging, mistake processing, etc. The targeted examples, carefully arranged contents and scientific learning sequence that the book offers guarantee beginners to understand object oriented idea deeply and attain proficiency fast. This book can be used as the teaching material of related course for computer public course teaching and undergraduate related course in higher learning institutions and also as reference book for readers learning Visual Basic.NET2010.