Eleven authorities from the University of Pittsburgh and the Children s Hospital of Pittsburgh link anatomy, physiology, pharmacology, neonatal medicine, and anesthetic practice in a single, definitive, well-referenced textbook of neonatal anesthesiology. There are substantive anatomic, physiologic, and pharmacologic differences between the infant or small child and the adult. Rapid, profound physiologic and pharmacologic changes occur during the neonatal period. Congenital anomalies that are incompatible with life unless surgically corrected are common, as are less life-threatening conditions; many infants are premature or small for their gestational age. Optimal care of the surgical neonate demands expeditious preoperative evaluation and resuscitation and refined, highly sophisticated intraoperative and postoperative care. Such care is best provided by pediatric anesthesiologists, pediatric surgeons, and pediatric intensivists working as colleagues. This book provides a sound scientific, clinical, and technical foundation for that effort. Neonatal physiology and pharmacology, the principles of neonatal anesthetic technique and their application to specific surgical conditions, and postoperative intensive care of the critically ill neonate are all discussed in considerable detail. Coverage includes cardiovascular physiology of the fetus and newborn, respiratory physiology, persistent pulmonary hypertension of the newborn, thermoregulation, parenteral fluid therapy, pediatric anesthetic pharmacology, pediatric breathing circuits, basic neonatal anesthesia and monitoring, common surgical conditions of the newborn, neonatal resuscitation, respiratory care, and ethics. Hardbound, 241 pp, illustrations.