This text, intended to be of use to pathologists, provides guidelines needed for the recognition and diagnosis of diseases of the liver. Highlights of this reference include: coverage of the history of liver biopsy; review of basic technical considerations; analyses of various liver biopsy techniques, including special methods such as histochemistry, immunohistochemistry, electron microscopy, chemical analysis and molecular techniques; effects of drugs on the liver; coverage of benign and malignant tumours; and liver transplantation. Further conditions and disorders of the liver are covered in chapters that include: congenital disorders of the liver; acute and chronic viral hepatitis; immune disorders of the liver; toxic liver disease; iron and copper metabolism disorders; non-viral hepatitis; alcoholic liver diseases; cirrhosis; and large bile duct disorders.