This book describes the modalities of treatment used in clinical management such as surgery, radiation and biological therapy and chemotherapy for all stages of disease. The treatment chapters follow a description of the biology of melanoma - epidemiology, genetics, tumour biology and immune response. Information from the treatment of over 20,000 cases around the world is incorporated, providing data on diagnosis and pathologic examinations. Natural history, prognosis and treatment results are supported by statistical data and new chapters are provided on such topics as dysplastic nevus syndrome, melanoma and pregnancy, biologic therapy, plastic surgical repairs, childhood melanomas, head and neck melanomas and subungual melanomas.