A wide variety of plastics is used in food-contact applications and it is important that such plastics do not affect the food with which they come into contact. Given the obvious importance of producing safe and wholesome food, with adequate shelf life, it is not surprising that the food industry is heavily regulated. There is considerable public concern about the safety of food packaging, and one issue is the potential migration of compounding ingredients, monomers or additives from plastics into food. In general, food diffuses into plastic packaging, enhancing the migration of unreacted monomers and potentially mobile additives from the plastic into the food. The objective of food packaging legislation is to protect the consumer by controlling the contamination of food by chemicals transferred from the packaging. Standard migration tests are available based on prescribed food simulants; these tests include overall migration testing and specific migration tests (for individual chemical species). The gradual development of lower detection limits for analytical methods has shown that many substances previously not considered as indirect food additives do actually migrate into food. Food packaging regulations are constantly under revision, and differ significantly between Europe and the USA - even between countries within the EU, although there is a strong harmonising influence from the Council of Europe and the European Commission. The regulation of food-contact materials in the EU is currently in a state of development, with various aspects still subject to national provisions until the European Commission has completed the harmonisation process. The US regulatory system is complex, with various approval and certification schemes. This Rapra Review Report provides a clearly written summary of the current legislation surrounding the use of plastics in contact with food. It will be of interest to those working to formulate food-contact plastics, food processors and