This volume explores foundational issues surrounding the interaction of religion and the academy in the 21st century. Featuring the work of 18 scholars from diverse institutional, disciplinary and religious backgrounds, this collection of essays issues from a three-year Lilly Seminar on religion and higher education. Reflecting the diversity of the seminar participants, this volume presents a wide variety of viewpoints on the role of religion in higher education and different approaches to religiously informed scholarship and teaching.