Revised and updated the Second Edition of this clinical reference provides comprehensive, current information on the immunologic mechanisms involved in conditions affecting the eye and on the varied clinical manifestations of these conditions. Dr. Friedlander reviews the basic principles of general and ophthalmic immunology and then discusses the full range of clinical entities in which these immunologic mechanisms play a significant role. The Second Edition"s coverage includes newly described entities such as AIDS, Lyme disease, and Acanthamoeba keratitis and incorporates new concepts on other local and systemic diseases. A chapter on immunologic mechanisms in corneal transplantation is also included.