This volume provides an in-depth view on the current state of research and clinical application of intravenous anaesthesia. It is divided into three sections with subjects on pharmacokinetic and dynamic modelling of anaesthetic action, monitoring and clinical application of intravenous anaesthesia and on the determination and meaning of effect sites of anaesthetic action. This volume is of great interest and education value to all professionals in the science of clinical application of intravenous anaesthesia.