Comprehensive information on the biology, ecology, and clinical aspects of these diseases. • Presents state-of-the-art information on disease epidemiology, transmission, and ecology. • Integrates divergent information relevant to the full spectrum of tick-borne diseases, incorporating tick biology and identification, distribution of the diseases ticks transmit, and various strategies for tick control. • Reviews the clinical approach to a patient with a possible tick-borne affliction. • Features in-depth profiles of specific diseases, including information on disease history, biology, epidemiology, ecology, transmission, clinical manifestations, diagnosis, treatment and prevention. • Examines the geographical distribution of tick-borne diseases and their vectors.