Horses get relief for up to two weeks per vial (6 vials included) from horn flies, face flies, stable and house flies, black flies, deer flies, horse flies, gnats, and mosquitoes. Additional benefits of Freedom 45 include: New improved formula with broader control. May be used on pregnant mares. Easy-to-use applicator with no-spill, resealable cap. 9 mL dosages for maximum effect. Water and perspiration resistant. A full 3 months of protection in each stable pack. Contains no dilemonine. Active Ingredients: permethrin 45%. Inert Ingredients: 55%. Products high level of permethrins (45%) makes it toxic to fish--should not be added to water. Not for use in foals under 3 months old. This product ships by Value Ground only. We are unable to deliver to P.O. boxes, APO/FPO addresses, Alaska, Hawaii, the Virgin Islands, Guam, or Canada.