Hank McCoy-Best of the X-Men-is in a quest to find a cure for the deadly Legacy virus that has been striking mutants all over the world, destroying their mutant powers¨or killing them outright. But Beast, and Moira MacTaggart-the only known infected human-find themselves becoming pawns in a power struggle pitting Sebastian Shaw of the Hellfire Club against Selene the Black Queen. And above it all, waiting to strike and put the threat of the Legacy virus to his own diabolical use is Magneto, the most dangerous mutant in the world.