100-percent natural, uniquely formulated with l-theanine, a naturally occurring amino acid in green tea that helps promote a restful relaxed state without causing reduced alertness. Relieves stress and anxiety in pets. Easy to use, simply apply directly or mix with food or a favorite treat. For best results use 30 minutes prior to stress-inducing events. Great for thunderstorms, fireworks, separation anxiety, car rides, and visits to the groomer or vet. Directions; cats 1/4 teaspoon twice a day, dogs under 25-pound 1/4 teaspoon twice a day; 26-50-pound 1/2 teaspoon twice a day; 51-75-pound 3/4 teaspoon twice a day and Over 75-pound 1 teaspoon twice a day. Active ingredients; l-theanine 100-mg 1/2 teaspoon, thiamine, niacin, coenzyme q-10, extracts of green tea, white tea and chamomile in purified water gel. 4-ounce a bottle.