Ruby Reef Rally is a copper free water treatment for the control and elimination of external parasites especially dinoflagellates, flukes and pathogenic bacteria in marine and freshwater aquaria. Rally is safe for reef, marine, freshwater and planted aquaria. It has been unequivocally proven to be safe for fish, corals, invertebrates and plants. This is safe and effective for rapid control of dangerous and destructive infestations such as marine velvet. It has a long shelf life at room temperature. Rally is safe for all fish, corals, invertebrates and macro algae, as well as the facultative anaerobes and nitrifying bacteria essential to biologic filtration. Rally safety and effectiveness has been widely proven in hobby and commercial applications. This can be used in combination with Kick-Ich or Sliminator. In fact, the simultaneous use of Kick-Ich and Rally is recommended when ich is present or may be present, with dinoflagellate diseases such as marine velvet or clown fish"s disease. The combined use of Kick-Ich and Rally is safe for all marine and reef aquaria. It can be used with phosphate and ammonia adsorbents, but not with activated carbon or related products. Use of compatible with most antibiotic regimens, but simultaneous use with other types of medications is not recommended. This is stable for at least one year if stored at room temperature and out of direct strong light. Do not freeze or store in the cold and don"t shake bottle prior to or during use and replace caps immediately after use. Turn off protein skimmers and UV sterilizers, also remove carbon filtration and any absorbent media that would remove Rally from the water. Dose on days 1, 2 and 3 for normal infections. For severe infection further dosing may be required. Add 1-ounce of per 5 and 10-gallons of total water volume including the filtration system for fresh water and reef tanks. Available in 2-liter bottle which treats 360-gallon.