1. introduction 2. Historical aspects 3. Epidemiology and pathological aspects 4. Clinico-radiological aspects 5. Clinical diagnosis 6. Osteonecrosis of femoral head 7. Osteonecrosis of the humeral head in Sickle cell haemoglobinopathy 8. Osteomyelitis in patients with Sickle cell haemoglobinopathy 9. Pathological fractures of long bones in patients with Sickle cell haemoglobinopathy 10. Hand-foot syndrome in patients with Sickle cell haemoglobinopathy 11. Vertebral changes in Sickle cell haemoglobinopathy 12. Growth disturbances in Sickle cell haemoglobinopathy 13. Sickle cell arthropathy (Joint manifestations in patients with Sickle cell haemoglobinopathy) 14. Sickle cell crisis 15. Other manifestations of Sickle cell haemoglobinopathy 16. Clinical and anthropometric studies in patients of Sickle cell haemoglobinopathies (Body shape, growth and development) 17. Anaesthesia care in surgical treatment for patients of Sickle cell haemoglobinopathy 18. Recommendations 19. Anthropometric data for males and females.