All natural, no preservatives, made in the USA. A complete food source for orphaned or rejected puppies or those nursing, but needing supplemental feeding. Also recommended for growing puppies or adult dogs that are stressed and require a source of highly digestible nutrients. Esbilac is a complete diet for puppies fortified with vitamins and minerals. Esbilac"s life saving formula closely matches bitch"s milk in protein and energy and has set the standard in canine neonatal nutrition for over 70 years. Powder formula is easy to mix with water.