This book is a comprehensive overview of current methodologies and technologies related to clinical biomarkers. It discusses biomarker discovery as a whole, rather than focusing on one specific marker or cancer. It also provides insights into the current technological platforms for biomarker discovery, including mass spectrometry combined with multidimensional chromatography, DIGE, and various chip technologies. The book consists of a series of comprehensive reviews written by world leaders in the field, providing authoritative and comprehensive coverage for professionals, students and scientists alike.