This book provides the first unified theory of nutrient deficiency and dependency since the idea was first broached by Linus Pauling in the 1960s. The world is now suffering a global vitamin B-3 deficiency and dependency pandemic, which is perhaps more devastating than the scurvy pandemic. The authors review research studies of vitamin B-3 dating back to the 1930s and show that large, controlled doses of vitamin B-3 are effective in preventing, treating, and even reversing vitamin B-3 deficiency and dependency related diseases.