Oratene has a combination of two unique enzymes, which is just what you need to effectively reduce plaque on your pet"s teeth. The drinking water additive contains Mutanase and Dextranase, which inhibit odor-causing microbes and the formation of plaque. And with the other antibacterial enzymes, you have a comprehensive dental care system for your pet! Simply add the flavorless concentrate to their drinking water to keep their teeth clean without brushing. The formula is pH neutral, with no xylitol, alcohol, chlorhexidine or chlorine compounds, so it"s 100% safe for daily ingestion.