Neuroblastomas are tumors of the sympathetic nervous system. Unfortunately, this group of tumors has not shown the same remarkable progress in cure rate that has been achieved in most other childhood malignancies and this is one of the reasons why neuroblastomas have been studied so extensively by pediatric oncologists worldwide. This book summarizes the current state-of-the-art of neuroblastoma biology and therapy. The international authorship of this book illustrates the global interest in neuroblastomas by pediatric oncologists, surgeons, radiologists, biologists, pathologists and others. As it addresses all major areas from basic science to late effects of treatment, it will be a useful resource to a wide range of individuals in basic research, clinical investigation and treatment.