Contains fluoride for cavity prevention and baking soda and calcium for clean teeth. We use natural ingredients in innovative ways without adding any artificial flavors, fragrances, colors, or preservatives. Fluoride helps remineralize soft spots on teeth before they turn into full fledged cavities and strengthens the tooth structure so enamel becomes more resistant to decay. This product does not contain saccharin; artificial sweeteners, preservatives, colors, or flavors, or animal ingredients. Tom"s of Maine products are tested for safety without the use of animals. Made in U.S.A.