Glucosamine Sulfate is a versatile compound involved in the formation of your nails, tendons, skin, eyes, bones, ligaments and heart valves. Glucosamine helps support the strength and integrity of joint structures throughout the body. MSM plays a key role in the formation of Di-sulfide bonds which aid in the structure of connective tissue. This compound is very beneficial as levels of MSM decrease with age. White Willow was used by Native Americans for many years in traditional medicine. The mechanism of salicin, a component of white willow, is related to acetyl salicidic acid, the active ingredient in aspirin. Bromelain has been used for many years to support healthy muscles and joints. Supporting blend: The stress of athletic events such as basketball, running, swimming, and jumping can cause inflammation in your joints and muscles. These powerful ingredients are formulated to support the integrity and heath of muscles and joints.