Pro-Gest Cream is a natural progesterone cream to help women maintain balance and harmony in life and with their bodies by offering support for the physical and emotional symptoms associated with menopause. Pro-Gest? cream is manufactured to contain 450 milligrams (mg) of USP Progesterone per ounce (900 mg per two-ounce tube). Each ? tsp contains approximately 20 mg of USP Progesterone. Careful clinical research has shown this to be an effective amount to achieve a natural balance. United States Pharmacopoeia (USP) Progesterone is progesterone that exactly duplicates the progesterone naturally produced in the body. It"s sometimes referred to as "human-identical" or "bio-identical" progesterone. The title "USP Progesterone" differentiates natural progesterone from synthetic progestins or progestogens