Corticool 1% Hydrocortisone Anti-Itch Gel formula, when tested against a 2.5% prescription hydrocortisone cream, penetrates 2.87 times better providing higher bioavailability of hydrocortisone. This means Corticool"s unique, fast-absorbing gel delivers more of the anti-itch active ingredients where you need it most on a hot, itchy, inflamed rash. Corticool"s menthol formula starts cooling and soothing immediately. With other hydrocortisone ointments or lotions, the active ingredient "floats" on the skin"s surface and can take 30 minutes or longer to stop your itch.