Dr. Arnold Katz"s internationally acclaimed classic is now in its thoroughly revised Fourth Edition, incorporating the latest molecular biology research and extensively exploring the clinical applications of these findings. In a readable style enhanced by more than 400 diagrams, Dr. Katz provides a comprehensive overview of the physiological and biophysical basis of cardiac function, beginning with structure and proceeding to biochemistry, biophysics, and pathophysiology in arrhythmias, ischemia, and heart failure. This edition features a new clinical applications section and expanded chapters on the ischemic heart and heart failure.