nbsp; The book has been developed in conjunction with NERS 462, a course offered every year to seniors and graduate students in the University of Michigan NERS program. The first half of the book covers the principles of risk analysis,nbsp;the techniques used to develop and update a reliability data base,nbsp;the reliability of multi-component systems,nbsp;Markov methods used to analyze the unavailability of systems with repairs,nbsp;fault trees and event trees used in probabilistic risk assessments (PRAs), and failure modes of systems. All of this material is general enough that it could be used in non-nuclear applications, although there is an emphasis placed on the analysis of nuclear systems. The second half of the book covers the safety analysis of nuclear energy systems,nbsp;an analysis of major accidents and incidents that occurred in commercial nuclear plants,nbsp;applications of PRA techniques to the safety analysis of nuclear power plants (focusing on a major PRA study for five nuclear power plants),nbsp;practical PRA examples,nbsp;and emerging techniques in the structure of dynamic event trees and fault trees that can provide a more realistic representation of complex sequences of events. The book concludes with a discussion on passive safety features of advanced nuclear energy systems under development and approaches taken for risk-informed regulations for nuclear plants.