ASHP’s Safety and Quality Pearls is one of the most popular sessions at the ASHP Midyear Clinical Meeting, and the 2007 and 2008 sessions were no different. The presenters outlined examples of creative approaches to improving patient safety and quality of care in various U.S. and foreign health systems. Now with in its second volume, ASHP’s Safety and Quality Pearls 2 pulls together 17 of the original presentations offered at these sessions. This compilation offers in-depth information that expands beyond the 5 minute pearls of wisdom to provide specific, practical advice on solutions from the perspective of pharmacists and technicians who are living with the realities of these medication use issues every day.Topics in this Pearls series include: The application of processes used in other disciplines The journey of solution discovery and implementation Inventive approaches to data and error management Themes on education, operational issues, therapeutic management, and best practices. The abundance of information presented by authors representing both large and small health systems, public and private institutions; academic medical centers; government health care facilities; and small outpatient clinics will inspire you to attempt similar interventions in your own institutions, if you haven’t already done so.