Coloplast Prep Medicated Protective Skin Barrier - Wipes Protective skin barrier creates a "second skin" wherever added protection is required. When applied, skin prep provides an invisible film around stomas, preventing irritation between pouch changes. Fast-drying, non-cracking, non-peeling formula allows skin to breathe. Available in wipes or as a dabber bottle. Coloplast Prep is ideal protection for peristomal skin and any area subject to irritation or denudement. Coloplast Prep protects the skin with a clear, yet visible shield that dries quickly and allows the skin to breathe.