Orajel Regular Strength Toothache Pain Relief is specially formulated to provide effective relief from toothache pain. Orajel Regular Strength Toothache Pain Relief Gel is perfect for those who do not want or need a higher concentration of medicine. The gel formulation allows for more control of product placement during application. Analgesics taken internally (such as Tylenol®, aspirin or Advil®) can take up to thirty minutes to be effective, but Orajel Toothache gel goes right to the source of the pain for instant relief.