CoQ10 can boost skin repair and regeneration and reduce free radical damage. CoQ10 is a small molecule that can relatively easily penetrate into skin cells. Hyaluronic Acid - Hyaluronic acid, or simply referred to as, occurs naturally in the body. As the levels of hyaluronic decrease it adversely impacts the skin"s ability to retain moisture, thus leading to those inevitable wrinkles. Hyaluronic acid is excellent for reducing the appearance of wrinkles for six months or more.