Forteo ,Avonex,Copaxone,Embrel,Humulin must stay between 36 - 46 degrees Fahrenheit and must NOT be frozen. For this medication we recommend the Small Med Cooler Package .This set up will maintain an average temperature of 40 degrees Fahrenheit for 14 hours in 90-degree heat, never dropping below 34 degrees and never exceeding 56 degrees.GMS Coolers are leak proof, sweat proof, and make traveling with medication safe and easy. To be sure that we are on track with the space you need to contain this medication properly and keep it between the instructed temperatures, please make sure that the medication you have will fit into our 7.5" x 2.5" diameter area as these are the inside dimensions of our medication container.