Biotene® with Calcium, the #1 recommended Mouthwash for Dry Mouth Care.Kills germs and refreshes without burning. It contains no saccharin. Naturally sweetened with Xylitol. Alcohol Free Imagine a mouthwash with a soothing, gentle feel containing beneficial antibacterial enzymes. A mouthwash that cleans and refreshes and helps in the healing of minor irritations. That mouthwash is Biotene®.Only Biotene® contains four Bio-Active Enzymes to boost and restore the defense system found in your saliva. Together they help provide harmful bacterial protection, naturally. Biotene® is specially formulated for individuals experiencing dry mouth or having oral irritations. Natural Enzymes: Lactoferrin, Lysozyme, Lactoperoxidase, Glucose Oxydase.