IO BIO-Spira Patented nitrifying bacteria make marine aquariums fish-safe instantly, Now available through distribution, BIO-Spira accelerates the establishment of the bio-filter in newly set-up saltwater aquariums, The live bacteria start working immediately to provide a safe and healthy environment for your fish without the long wait, BIO-Spira can also be used after a water change, when adding new fish or after medicating, Live nitrifying bacteria start working immediately to reduce dangerous ammonia and nitrite, BIO-Spira prevents new tank syndrome for healthy fish, The patented mix of Nitrococcus, Nitrosomonas, Nitrosospira and Nitrospira is proven to work, Shelf stable formula, 12 months, requires no refrigeration (acceptable temperature, 35º to 90ºF) for added convenience, SKU: RYLHC2602