It takes two squirts of any other national brand to kill as many germs as one squirt of Purell Advanced Hand Sanitizer Refereshing Aloe . Formulation matters. Purell Advanced Hand Sanitizer Refereshing Aloe is skin friendly and mild on hands. It"s enhanced with four nourishing skin-conditioning agents. · Kills more than 99.99% of germs · More effective formula · Clinically proven effective in helping to maintain skin health · Enhanced with 4 nourishing skin-conditioning agents