Nattokinase is an enzyme derived from boiled soybeans and Bacillus natto. Research has shown nattokinase supports the body in breaking up and dissolving unhealthy coagulation of blood and supports fibrinolytic activity. These actions support overall good circulation and thus cardiovascular health. Every tissue in your body relies on your heart to circulate blood through all the blood vessels in your body in order to deliver nutrients and clear waste. How Natto-Z Works Healthy circulation occurs when your blood flows smoothly. Nattokinase doesn"t inhibit blood clot formation; it actually works to support healthy circulation by assisting the fibrinolytic blood clearing system, which breaks down cross-linked fibrin protein deposits in the blood.Healthy circulation can do wonders to support total health. When circulation is not balanced, tissues don"t get enough nutrients and blood does not clear enough wastes away. Systemic enzymes such as nattokinase support healthy circulation so that tissues can get the nutrients delivered and wastes removed - the way healthy blood circulation should work in the body.