This second edition of the landmark 1991 text, Basic Mechanisms of Pediatric Respiratory Disease reviews the importance of the integrations of molecular, cellular and physiologic strategies in the development of a new understanding of pediatric respiratory disorders. It provides state-of-the-art information about fundamental mechanisms underlying the pathogenesis and pathophysiology of lung disease in children. Incorporating a multidisciplinary approach and an integration of basic and clinical science, the text brings together diverse clinical disciplines related to lung disease such as neonatology, critical care medicine, allergy and immunology, and pediatric respiratory medicine. In addition, it seeks to integrate diverse basic science approaches including molecular biology, cell biology, genetics, developmental biology and cell physiology.