Therapik® is based on a very simple, scientifically proven principle. Most insect venom is thermolabile (sensitive to heat). Therapik®"s patented technology delivers heat in the specific temperature range necessary to neutralize the venom from over 20,000 different species of insects and sea creatures.The Therapik Mosquito Bite Relievers help provide instant relief from the pain and itch experienced from mosquito bites, bee stings, fire ants, jellyfish stings, and bites from up to 20,000 other species of insects. This 9V battery mosquito bite reliever is a handheld device that creates a soothing heat that, when applied to the affected area, relieves pain and itch from insect bites and stings. Use these handheld mosquito bite relievers for immediate relief.