Vicks Sinex 12 Hour Decongestant Ultra Fine Mist Moisturizing nasal spray provides temporary relief—up to 12 hours—for nasal congestion due to colds, hay fever, and upper respiratory allergies. Temporarily relieves nasal congestion due to colds, hay fever or upper respiratory allergies. Relieves sinus pressure and shrinks swollen nasal membranes so you can breathe more freely Vicks Sinex 12 Hour contains an effective decongestant for fast, long lasting relief of nasal stuffiness.