Twenty-something Luciano Gauna is odd. A failing screenwriter in Buenos Aires, Luciano lives in a state of paranoia, afraid of everything from STDs to his doorman. When his childhood friend Manuel, a very successful TV producer, returns from Madrid with his stunning new girlfriend Sofia, his world is thrown into a desperate funk. He discovers that Manuel has unflatteringly modeled him as the lead character on a successful Spanish TV show called The Paranoids, which Manuel is now bringing to Argentina. When Manuel leaves on a business trip to Chile, Luciano s remaining grip on reality unravels when he s left alone with Sofia and her alluring charm.