Dedicated FBI agent, Don Eppes recruits his mathematical-genius brother Charlie to help the Bureau solve a wide range of challenging crimes in Los Angeles. The two brothers take on the most confounding criminal cases from a very distinctive perspective. Inspired by actual cases, the series depicts how the confluence of police work and mathematics provides unexpected revelations and answers to the most perplexing criminal questions. Don deals in hard facts and evidence, whereas Charlie, a math professor, functions in a world of mathematical probability and equations. Now, despite their disparate approaches to life, Don and Charlie are able to combine their areas of expertise and solve some killer cases.