In Lifestage 1, when estrogen levels are high (usually between the ages of 15 and 40), it"s important to get your nutritional framework in order, set up a strong base for your bones, and balance your hormones naturally.Seek Comfort in PMS Symptom Free Chaste tree berry extract supports healthy hormone balance Calcium, magnesium and vitamin D work together to help provide relief of PMS symptoms DIM (dindolylmethane) helps support healthy estrogen metabolism