Cognitex is formulated to take advantage of the latest developments and ingredients for cognitive health. The latest ingredient in the Cognitex formula is uridine-5-monophosphate, a critical brain nutrient.13 Uridine-5-monophosphate (UMP) is a basic building block of RNA and DNA as well as of phosphatides such as phosphatidylcholine that are critical to optimal brain function and the health of neuronal cell membranes. Naturally found in the milk of nursing mothers, UMP is essential not only for the growth and development of infant brains, but also for healthy cognitive function in aging adults.14,15 Dietary supplementation with UMP may increase brain acetylcholine and phosphatide levels, and enhance some cholinergic functions.16The Cognitex formula provides other critical extracts that support healthy brain function, such as blueberry standardized with both anthocyanins and pterostilbene.Blueberry anthocyanins are considered one of natures most potent antioxidants and have demonstrated properties that extend well beyond suppressing free radicals.17,18 Pterostilbene, the other blueberry constituent, helps maintain healthy lipid and glucose levels in those already within normal range.19 Importantly, through their unique biological effects, pterostilbene and anthocyanins may help support DNA structure.20A crucial building block in the brain is phosphatidyl-serine (PS). In fact, brain tissues are especially rich in this nutrient. However, aging causes a decline in the PS content of cells throughout the body including brain cells, which can lead to cognitive decline. Phosphatidylserine helps the brain use its fuel efficiently. By boosting glucose metabolism and stimulating production of acetylcholine, supplemental phosphatidylserine has been shown to improve the condition of patients experiencing age-associated memory impairment or cognitive decline.10,12 Thus, replacing this brain food is essential.